Your Brain’s Chill Switch: A Guide to GABA Receptors

Your Brain’s Chill Switch: A Guide to GABA Receptors

Did you know that your brain has its own natural ‘chill switch’?

That switch is powered by GABA and its receptors. These tiny but mighty brain components are what help you slow down, relax, and find calm. Understanding how they work opens the door to a new, smarter way to unwind.

What is a GABA Receptor?

Imagine GABA as a calming radio signal and the GABA receptor as the antenna it’s picked up by. GABA (short for gamma-aminobutyric acid) is the brain’s primary inhibitory neurotransmitter. That means it sends a “slow down” signal to the brain, helping create calm, quiet racing thoughts, and relax tense muscles. GABA receptors are special proteins found on the surface of neurons—the brain’s messaging cells. When GABA arrives and binds to its receptor, it makes that neuron less likely to “fire.” In simple terms: the message is received, and the brain starts to relax. These receptors are found throughout your central nervous system, working tirelessly to maintain balance in your mental and physical state.

How GABA Receptors Function

We could also think of GABA and its receptor as a lock-and-key mechanism. GABA is the key, and when it fits into the receptor lock, the neuron calms down. This is how your brain naturally stops things from spiralling into overdrive. There are two main types of GABA receptors: GABA-A and GABA-B. GABA-A receptors are fast-acting and crucial for that immediate wave of relaxation. SENTIA is crafted to work specifically with these GABA-A receptors to deliver sociability and serenity without alcohol.

The Structure of GABA-A Receptors

GABA-A receptors aren’t simple switches—each receptor is made up of multiple components called subunits, and each subunit can tweak the final effect. This is why different GABA-activating substances can have very different results. Some might make you sleepy, while others simply help you relax and connect. This fine-tuned complexity is exactly what inspired Professor David Nutt’s approach to SENTIA’s formulation: targeted, not sedating.

Alcohol’s Effect on GABA Receptors (and Why There’s a Better Way)

An agonist is a chemical that binds to a receptor on a neuron and activates it, mimicking the effect of a natural neurotransmitter like GABA. Alcohol is a GABA-A receptor agonist. That’s why, after a drink or two, you may feel more relaxed or sociable—it boosts the natural calming action of GABA. But alcohol isn’t subtle. It’s a blunt instrument that floods your brain, reducing inhibition but also impairing judgment, coordination, and memory. At higher doses, it can lead to sedation, unconsciousness, and worse. It dulls everything—good and bad.But what if you could get the good without the bad?

SENTIA: Expertly Crafted to Enhance Your GABA System

SENTIA was born from a simple but powerful idea: to find a better way to unwind.  Developed by Professor David Nutt and a team of leading neuroscientists, SENTIA is a functional spirit designed to support the GABA system. Unlike substances that act as GABA agonists (which directly activate the receptor, like alcohol, SENTIA’s active ingredients are known as positive allosteric modulators (PAMs) of the GABA-A receptor.

This means they don’t switch the system on by themselves. Instead, they bind to a different part of the receptor and boost the calming effect of GABA when it’s naturally released in the brain—like turning up the volume on the body’s own signal, rather than pressing play.

Because PAMs only work when GABA is already present, they offer a gentler, more targeted way to enhance relaxation—making them a smarter, safer alternative to alcohol.

This isn’t just another herbal drink. It’s a precise, scientifically-backed formula designed to help you relax, open up, and connect—without alcohol, hangxiety, or compromise.

Feel the Connection. Find Your Flow.

With SENTIA, you can tap into your brain’s natural relaxation system and experience a more conscious kind of calm.

Explore GABA Red, GABA Gold and GABA Black—and discover the future of functional spirits.

Sentia Spirits
Written by Sentia Spirits
25th August 2025
GABA Labs
Scientifically reviewed by GABA Labs
26th August 2025

SENTIA SPIRITS: CRAFTED FOR CONNECTION

SENTIA Spirits are not just another range of non-alcoholic drinks. This is a new category entirely plant-based functional drinks designed to help you feel just right.

Whether you’re hosting friends, easing into the evening, or winding down on your own, SENTIA Spirits are crafted for connection and calm.

GABA Red 50cl

GABA Red 50cl

Find Your Vibe

£32.00

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GABA Gold 50cl

GABA Gold 50cl

FInd Your Smiles

£32.00

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GABA Black 50cl

GABA Black 50cl

Find Your Zone

£32.00

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Unwind, connect, and feel good, without compromising your clarity, wellness, or tomorrow.

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